Overview of Picked Chemical Compounds and Intermediates

Overview of Picked Chemical Compounds and Intermediates

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1. Pharmaceutical Intermediates
Bortezomib Acid Impurity: This is certainly an impurity related to bortezomib, a proteasome inhibitor used in the therapy of numerous myeloma. Its synthesis or analyze is very important for guaranteeing the purity and basic safety in the drug.
Abiraterone Acetate Intermediate (CAS NO. 122111-01-7): A precursor in the synthesis of abiraterone acetate, a drug Utilized in the treatment of prostate most cancers by inhibiting androgen manufacturing.
Imatinib Intermediate (CAS NO. 152460-ten-1): A key compound during the synthesis of imatinib, a drug that targets distinct forms of most cancers, like chronic myelogenous leukemia (CML).
Docetaxel Intermediate: A compound Employed in the synthesis of docetaxel, a chemotherapy medication that treats numerous cancers which include breast, lung, and prostate cancer.
2. Chemical Impurities and Byproducts
GeMcitabine Intermediates (T6, T9, eight): These are intermediates while in the synthesis of gemcitabine, an anti-most cancers drug. Their research is important for optimizing the creation procedure and guaranteeing higher purity.
Lapatinib Intermediate (CAS NO. 231278-eighty four-five): Lapatinib is utilized to deal with breast most cancers, and these intermediates are linked to its manufacturing.
Fulvestrant Intermediates: Fulvestrant can be an estrogen receptor antagonist used in the therapy of breast most cancers. Many intermediates OTAVA-BB1207229 help in the synthesis of this drug.
Paclitaxel Aspect Chain Acid (CAS NO. 949023-16-nine): This intermediate is Employed in the synthesis of paclitaxel, a chemotherapy drug effective in dealing with cancers which include ovarian, breast, and lung cancer.
three. Other Noteworthy Compounds
Irinotecan Hydrochloride Trihydrate (CAS NO. 136572-09-three): A chemotherapy drug Employed in the therapy of colorectal cancer and modest cell lung most cancers.
3-Amino-1-hydroxyadamantane (CAS 702-82-9): This compound is involved with the synthesis of adamantane derivatives, that have many programs, like antiviral Houses.
Vildagliptin Intermediates: Used in the production of vildagliptin, an oral drug for kind 2 diabetes that inhibits the enzyme DPP-four to control blood sugar concentrations.
four. Miscellaneous Compounds
D-Gluconic Acid δ-Lactone (CAS NO. 61259-forty eight-1): This compound is associated with the synthesis of varied gluconic acid derivatives, that happen to be Utilized in foodstuff, pharmaceutical, and industrial programs.
Canagliflozin Intermediate 2: tert-butyl 4-(6-aminopyridin-3-yl)piperazine-1-carboxylate A precursor within the synthesis of canagliflozin, a medication utilized to manage type two diabetic issues by inhibiting sodium-glucose co-transporter 2 (SGLT2).